Frédéric Chavane

Chargé de Recherche à l'INCM, Equipe DyVA
UMR 6193, CNRS & Université de la Méditerranée
31 chemin J. Aiguier (Bât N, salle 030)
13402 Marseille Cedex 20
Phone: 33 (0)4 91 16 43 14
Fax: 33 (0)4 91 77 49 69

Email: Frederic.Chavane_at_incm.cnrs-mrs.fr

Research interests

The main line of my research is the study of the functional role of horizontal cortical interactions.
Our perception and our actions are constantly under the influence of spatio-temporal contextual interactions. If visual cortical neurons see only a small part of the image, they are also interacting over large intracortical distances through horizontal axons, generating important lateral interactions. Real-time optical imaging offers, for the first time, the possibility to record lateral intracortical dynamics over large cortical territories. Using this technique, we investigate the functional role of cortical horizontal interactions in the emergence of a percept or an action in the awake, behaving monkey.

Collaborations

My main collaborations are with the group of Yves Frégnac (UNIC, Gif-sur-Yvette, France) and with Dirk Jancke (Bochum, Germany). Starting in 2005, those collaborations will be financed by the FACETS project (E.U. VIth Framework, Future and Emerging Technologies)

I also have collaborations with the group of Amiram Grinvald (Rehovot, Israel)

Publications

• Chemla, S; Chavane, F (2010), « A biophysical cortical column model to study the multi-component origin of the VSD signal.  », NeuroImage, (in press)
• Reynaud, A; Takerkart, S; Masson, GS; Chavane, F (2010), « Linear model decomposition for voltage-sensitive dye imaging signals : application in awake behaving monkey », NeuroImage , (in press)
• Takerkart, S; Fenouil, R; Piovano, J; Reynaud, A; Hoffart, L; Chavane, F; Papadopoulo, T; Conrath, J; Masson, GS (2008), « A quantification framework for post-lesion neo-vascularization in retinal angiography », Proceedings of the 5th International Symposium on Biomedical Imaging, Paris,
• Hoffart, L; Conrath, J; Matonti, F; Galland, F; Wotawa, N; Chavane, F; Castet, E; Ridings, B; Masson, G.S (2007), « Étude en IRM fonctionnelle 3T de l’organisation rétinotopique du cortex visuel  », J Fr. Ophtalmol., 30, 8, 830-836
• Reynaud, A; Barthélemy, F; Masson, GS; Chavane, F (2007), « Input-output transformation in the visuo-oculomotor network », Arch Ital Biol, 145
• Sharon, D.; Jancke, D.; Chavane, F.; Naaman, S.; Grinvald, A. (2007), « Cortical Response Field Dynamics in Cat Visual Cortex », Cerebral Cortex, PDF
• Goffart, L; Quinet, J; Chavane, F; Masson, GS (2006), « Influence of Background Illumination on Fixation and Visually-guided saccades in the rhesus monkey », Vision Research, 46: 149-162 PDF
• Jancke, D ; Chavane, F ; Naaman, S ; Grinvald, A (2004), « Imaging cortical correlates of illusion in early visual cortex », Nature, 428: 423-426 PDF
• Frégnac, Y ; Monier, C ; Chavane, F ; Baudot, P ; Graham, L (2003), « Shunting inhibition, a silent step in visual computation », Journal of Physiology 97, 441-451 PDF
• Monier, C; Chavane, F; Baudot, P; Graham, LJ; Frégnac, Y (2003), « Orientation and direction selectivity of synaptic inputs in visual cortical neurons: A diversity of combinations produces spike tuning. », Neuron, 37, 663-680 PDF
• Chavane, F; Monier, C; Bringuier, V; Baudot, P; Borg-Graham, L; Lorenceau, J; Fregnac, Y (2000), « The visual cortical association field: a Gestalt concept or a psychophysiological entity? », J. Physiol. Paris, 94(5-6):333-42. PDF
• Bringuier, V; Chavane, F; Glaeser, L; Frégnac, Y (1999), « Horizontal propagation of visual activity in the synaptic integration field of area 17 neurons. », Science, 283, 695-699 PDF
• Fregnac, Y; Bringuier, V; Chavane, F (1996), « Synaptic integration fields and associative plasticity of visual cortical cells in vivo. », J. Physiol. Paris, 90(5-6):367-72.
• Fregnac, Y; Bringuier, V; Chavane, F; Glaeser, L; Lorenceau, J. (1996), « An intracellular study of space and time representation in primary visual cortical receptive fields. », J. Physiol. Paris, 90(3-4):189-97. Review