Un Institut à l'interface entre la recherche fondamentale et la recherche clinique sur le fonctionnement normal et pathologique du cerveau.

L'Institut de Neurosciences Cognitives de la Méditerranée (INCM) est une unité mixte de recherche (UMR) créée par le CNRS et l'Université de la Méditerranée. Notre principal objectif est de développer des recherches interdisciplinaires, à l'interface entre les approches fondamentale et clinique, sur les mécanismes cérébraux de la perception, les émotions, la cognition et l'action.

Le programme de recherche de l'Institut repose sur 5 atouts majeurs :

1. Un concept de traitements neuronaux dynamiques, dépendants du contexte
2. Interdisciplinarité de proximité
3. Une concentration unique de spécialistes en primates non humains
4. Une interaction étroite entre chercheurs et cliniciens, et
5. Des plates formes technologiques modernes (plate forme IRMf 3T, Imagerie optique chez le primate vigile, Systèmes d'enregistrements multi-electrodes, la stimulation magnétique transcrânienne, MEG et EEG).

Driss Boussaoud

Sélection de publications

• Perrinet L. (2010), «Role of homeostasis in learning sparse representations», Neural Computation, in press
• Guerrasio, L; Quinet, J; Büttner, U; Goffart, L (2010), «The fastigial oculomotor region and the control of foveation during fixation», Journal of Neurophysiology , in press
• Ponce-Alvarez, A; Kilavik, BE; Riehle, A (2009), «Comparison of local measures of spike time irregularity and relating variability to firing rate in motor cortical neurons», Journal of Computational Neuroscience, in press
• Rickert,J; Riehle, A; Aertsen, A; Rotter, S;Nawrot, MP (2009), «Dynamic encoding of movement direction in motor cortical neurons», Journal of Neuroscience, 29: 13870-13882
• Kilavik, BE; Roux,S;Ponce-Alvarez, A;Confais,J;Grün,S;Riehle, A (2009), «Long-term modifications in motor cortical dynamics induced by intensive practice», Journal of Neuroscience, 29: 12653-12663
• Quinet, J; Goffart, L (2009), «Electrical microstimulation of the fastigial oculomotor region in the head unrestrained monkey», Journal of Neurophysiology , 102: 320-336, 2009.
• Hafed, Z.M; Goffart, L; Krauzlis, R.J (2009), «A neural mechanism for microsaccade generation in the primate superior colliculus», Science, 323: 940-943
• Longcamp, M; Boucard, C; Gilhodes, J.C; Nazarian, B; Anton, J.L; Roth, M; Velay, J.L (2008), «Learning through hand- or type-writing influences visual recognition of new graphic shapes: behavioral and functional imaging evidences», Journal of Cognitive Neuroscience, 20(5) 802-15
• De Graaf, J; Frolov, A; Fiocchi, M; Nazarian, B; Anton, J.L; Pailhous, J; Bonnard, M (2008), «Preparing for a motor perturbation : early implication of primary motor and somatosensory cortices.», Human Brain Mapping, in press
• Brovelli, A; Laksiri, N; Nazarian, B; Meunier, M; Boussaoud, D (2008), «Understanding the neural computations of arbitrary visuomotor learning through fMRI and associative learning theory », Cereb Cortex, 18(7):1485-95
• Barthélemy, F; Perrinet, LU;Castet, E; Masson, GS (2008), «Dynamics of distributed 1D and 2D motion representations for short-latency ocular following», Vision Research, 48(4):501-22
• Schön, D; Boyer, M; Moreno, S; Besson, M; Peretz, I; Kolinsky, R (2008), «Songs as an aid for language acquisition», Cognition , 975–983
• Wicker, B; Fonlupt, P; Hubert, B; Tardif, C; Gepner, B; Deruelle, C (2008), «Abnormal cerebral effective connectivity during explicit emotional processing in adults with autism spectrum disorder», Social Cognitive and Affective Neuroscience, sous presse
• Nawrot, MP; Boucsein, C; Rodriguez Molina, V; Riehle, A; Aertsen, A; Rotter, S (2008), «Measurements of variability dynamics in cortical spike trains», J Neurosci Methods, 169: 374-390
• Hafed, Z; Goffart, L; Krauzlis, R (2008), «Superior colliculus inactivation causes stable offsets in eye position during tracking», Journal of Neuroscience , 28 : 8124-8137
• Parron, C; Deruelle, C; Fagot, J (2007), «Processing of biological motion point-light displays by baboons (Papio papio)".», Journal of Experimental Psychology:Animal Behavior Processes., 33, 381-391
• Denker, M; Roux, S; Timme, M; Riehle, A; Grün, S (2007), «Phase synchronization between LFP and spiking activity in motor cortex during movement preparation», Neurocomputing, 70: 2096-2101
• Sharon, D.; Jancke, D.; Chavane, F.; Naaman, S.; Grinvald, A. (2007), «Cortical Response Field Dynamics in Cat Visual Cortex», Cerebral Cortex,
• Santos, A; Rondan, C; Rosset, D; Da Fonseca, D; Deruelle, C (2007), «Mr. Grimace or Ms. Smile: Does categorization impacts perceptual processing in autism?», Psychological Science, 19, 70-76
• Bonnard, M; Galléa, C; de Graaf, J; Pailhous, J (2007), «Corticospinal control of the thumb-index grip depends on precision of force control : a TMS and fMRI study in humans. », European Journal of Neuroscience, 25 (3), 872-880
• Magne, C; Astésano, C; Aramaki, M; Ystad, S; Kronland-Martinet, R ; Besson, M (2007), «Influence of syllabic lengthening on semantic processing in spoken French: Behavioural and electrophysiological evidence», Cerebral Cortex: Advance access, published January 30, 2007,
• Meunier, M; Monfardini, E; Boussaoud, D (2007), «Learning by observation in rhesus monkeys», Neurobiology of Learning and Memory, 2, 243-8
• Kaladjian; A, Jeanningros, R; Azorin, JM; Grimault, S; Anton, JL; Mazzola-Pomietto, P (2007), «Blunded activation in right ventrolateral prefrontal cortex during response inhibition in schizophrenia», Schizophr Res., 97: 184-193
• Bernard, J-B; Scherlen, A-C; Castet, E (2007), «Page mode reading with simulated scotomas: A modest effect of interline spacing on reading speed», Vision Research, 47(28) , 3447-3459
• Quinet, J; Goffart, L (2007), «Head unrestrained gaze shifts after muscimol injection in the caudal fastigial nucleus of the monkey», Journal of Neurophysiology, 98 : 3269–3283